Duke Criteria (Modified Duke) Calculator

Duke Criteria (Modified Duke) Calculator: Explanation and Clinical Context The Modified Duke Criteria is a widely accepted clinical tool for diagnosing infective endocarditis (IE) based on a combination of major and minor criteria. Major criteria include positive blood cultures and evidence of endocardial involvement via echocardiography. Minor criteria include predisposing heart conditions or IV drug use, fever >38°C, vascular phenomena (e.g., arterial emboli, Janeway lesions), immunologic phenomena (e.g., Osler nodes, Roth spots), and microbiologic evidence not meeting major criteria.

Definite IE is diagnosed if there are either 2 major criteria, 1 major plus 3 minor criteria, or 5 minor criteria. Possible IE is considered with 1 major plus 1–2 minor criteria, or 3–4 minor criteria. This calculator helps clinicians quickly stratify patients for further diagnostic work-up and management planning.