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Glenn Procedure Risk Model

: Explanation & Clinical Context This model estimates the probability of having a complicated Glenn procedure (cGP) after a bidirectional Glenn operation. The cGP concept is derived from Khaira et al (2023), where they defined a composite endpoint of mortality or significant postoperative complications by 2 years. In their multivariable analysis, higher inotrope score on postoperative day 1 (HR ≈ 1.04 per unit) and u

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Glenn Procedure Risk Model: Explanation & Clinical Context This model estimates the probability of having a complicated Glenn procedure (cGP) after a bidirectional Glenn operation. The cGP concept is derived from Khaira et al (2023), where they defined a composite endpoint of mortality or significant postoperative complications by 2 years. In their multivariable analysis, higher inotrope score on postoperative day 1 (HR ≈ 1.04 per unit) and use of inhaled nitric oxide (iNO) (HR ≈ 7.31) were independent predictors of cGP.

This calculator uses a simplified additive linear model: a baseline risk (5 %) plus incremental risk from inotrope score and an additional jump if iNO was used. This tool is not validated, and should be used only for educational or exploratory purposes. Clinical decision-making should rely on full multivariable risk models and expert judgment.

Evidence & references2 primary sources mapped
  1. Source 1

    Khaira GK, et al. A complicated Glenn procedure: risk factors and association with adverse long-term neurodevelopmental and functional outcomes. Cardiology in the Young.

  2. Source 2

    doi:10.1017/S104795112200261X

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Active local worksheet: mapped inputs can be completed, validated, copied, saved, and exported on this device. No numerical score is asserted unless its formula is independently reproducible.

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.