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HCM Risk-SCD 2.0 Calculator

HCM Risk-SCD 2.0 (ESC 2023 Update): Explanation and Clinical Context The HCM Risk-SCD 2.0 score is a validated tool to estimate the 5-year risk of sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). It integrates clinical, echocardiographic, and family history parameters, including age, maximal left ventricular wall thickness, left atrial diameter, maximal LV outflow tract gradient, family

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HCM Risk-SCD 2.0 (ESC 2023 Update): Explanation and Clinical Context The HCM Risk-SCD 2.0 score is a validated tool to estimate the 5-year risk of sudden cardiac death (SCD) in patients with hypertrophic cardiomyopathy (HCM). It integrates clinical, echocardiographic, and family history parameters, including age, maximal left ventricular wall thickness, left atrial diameter, maximal LV outflow tract gradient, family history of SCD, non-sustained ventricular tachycardia, unexplained syncope, and presence of apical aneurysm. The score categorizes patients into low (<4%), intermediate (4–6%), or high risk (>6%) for SCD at 5 years, guiding decisions for implantable cardioverter-defibrillator (ICD) implantation for primary prevention.

Accurate risk prediction allows individualized patient management, informed clinical decision-making, and prioritization of high-risk patients for prophylactic therapy.

Evidence & references1 primary source mapped
  1. Source 1

    O'Mahony C, et al. A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy (HCM Risk-SCD). Eur Heart J. 2014;35:2010–2020. Updated ESC Guidelines for HCM, Eur Heart J. 2023;44:3123–3203.

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.