LAA Thrombus Detection Index (TEE-based, CLOTS-AF) Calculator

LAA Thrombus Detection Index (TEE-based, CLOTS-AF): Explanation and Clinical Context The CLOTS-AF score estimates the probability of left atrial appendage thrombus (LAAT) before cardioversion or ablation in atrial fibrillation or flutter, integrating six routinely measured parameters: serum creatinine, LVEF, LAVI, TAPSE, prior ischemic stroke/TIA, and rhythm at imaging. This index was derived in patients undergoing TEE-guided cardioversion and demonstrated strong discrimination for LAAT or dense spontaneous echo contrast (AUC ≈ 0.82). Clinical interpretation: - Higher scores indicate greater probability of LAAT. - A low score suggests low likelihood of thrombus formation, whereas a high score indicates substantial risk and the need for continued anticoagulation or repeat imaging before cardioversion. - Always combine this index with guideline-based anticoagulation, imaging, and clinical assessment.