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MADIT II Risk Score Calculator

MADIT II Risk Model: Explanation and Clinical Context The MADIT II Risk Score is a validated tool designed to estimate the 2-year mortality risk in patients with ischemic cardiomyopathy and severely reduced left ventricular ejection fraction (<30%). It uses easily obtainable clinical variables including age >70 years, NYHA functional class >I, presence of diabetes, QRS duration >120 ms, atrial fibrillation, BUN >26 m

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MADIT II Risk Model: Explanation and Clinical Context The MADIT II Risk Score is a validated tool designed to estimate the 2-year mortality risk in patients with ischemic cardiomyopathy and severely reduced left ventricular ejection fraction (<30%). It uses easily obtainable clinical variables including age >70 years, NYHA functional class >I, presence of diabetes, QRS duration >120 ms, atrial fibrillation, BUN >26 mg/dL, and resting heart rate >75 bpm. The total score stratifies patients into low, moderate, or high risk categories, guiding clinicians in prognostication and management decisions such as consideration for implantable cardioverter-defibrillator (ICD) therapy.

Evidence & references1 primary source mapped
  1. Source 1

    Moss AJ, et al. "Risk stratification in MADIT II: development of a clinical score." J Am Coll Cardiol. 2004;44:1840-1846. doi:10.1016/j.jacc.2004.07.037

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Active local worksheet: mapped inputs can be completed, validated, copied, saved, and exported on this device. No numerical score is asserted unless its formula is independently reproducible.

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.