Clinical inputs
Understand the result,
not just the number.
MADIT II Risk Model: Explanation and Clinical Context The MADIT II Risk Score is a validated tool designed to estimate the 2-year mortality risk in patients with ischemic cardiomyopathy and severely reduced left ventricular ejection fraction (<30%). It uses easily obtainable clinical variables including age >70 years, NYHA functional class >I, presence of diabetes, QRS duration >120 ms, atrial fibrillation, BUN >26 mg/dL, and resting heart rate >75 bpm. The total score stratifies patients into low, moderate, or high risk categories, guiding clinicians in prognostication and management decisions such as consideration for implantable cardioverter-defibrillator (ICD) therapy.
- Source 1
Moss AJ, et al. "Risk stratification in MADIT II: development of a clinical score." J Am Coll Cardiol. 2004;44:1840-1846. doi:10.1016/j.jacc.2004.07.037
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