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ACS-MCS (Mechanical Circulatory Support) Score: Explanation and Clinical Context The ACS-MCS score is a simple, four-point risk score developed to predict 30-day all-cause mortality in patients with cardiogenic shock due to acute coronary syndrome who require short-term mechanical circulatory support (ST-MCS). The model assigns 1 point each for: age > 60 years, pre-ST-MCS lactate > 2.5 mmol/L, presence of acute kidney injury (AKI) at the time of ST-MCS implementation, and SCAI cardiogenic shock stage E (extremis). Total score ranges 0–4 and stratifies patients into low (0–1), intermediate (2), and high (3–4) risk groups.
The score was derived and internally validated using the UCAR Shock database (n=159), demonstrated good calibration and discrimination (AUC ≈ 0.80), and may assist clinicians in early risk stratification and device selection as an adjunct to clinical judgment.
Evidence & references2 primary sources mapped
- Source 1
Marashly Q, Taleb I, Kyriakopoulos CP, et al. Predicting mortality in cardiogenic shock secondary to ACS requiring short-term mechanical circulatory support: The ACS-MCS score. Catheter Cardiovasc Interv. 2021;98(7):1275–1284. DOI:10.1002/ccd.29581. SCAI Expert Consensus Statement on the Classification of Cardiogenic Shock (Baran DA et al.,
- Source 2
— SCAI SHOCK stages A–E. KDIGO AKI Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury (2012) — for AKI diagnostic criteria and staging.
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