Metabolic Syndrome Diagnostic Criteria Calculator

Metabolic Syndrome Diagnostic Criteria Explanation and Clinical Context Metabolic syndrome represents a clustering of interrelated metabolic abnormalities that increase the risk of cardiovascular disease and type two diabetes. The diagnostic criteria used in this tool follow the Adult Treatment Panel Three guidelines which define metabolic syndrome as the presence of at least three of five components. These include abdominal obesity measured by waist circumference elevated triglycerides low HDL cholesterol elevated blood pressure and elevated fasting plasma glucose.

Each component reflects an underlying pathophysiologic process such as insulin resistance endothelial dysfunction or chronic low grade inflammation which together amplify long term cardiometabolic risk. Identification of metabolic syndrome supports early lifestyle intervention and targeted medical therapy to reduce progression into overt cardiovascular disease and diabetes. Reference Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults.

Executive Summary of The Third Report of The National Cholesterol Education Program Adult Treatment Panel Three. JAMA. 2001.