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Neonatal Pulmonary Hypertension (NPH) Risk Index Calculator

Neonatal Pulmonary Hypertension (NPH) Risk Index: Explanation and Clinical Context The Neonatal Pulmonary Hypertension Risk Index is a validated scoring system designed to stratify the risk of pulmonary hypertension in neonates, particularly preterm infants. It incorporates key clinical variables available shortly after birth, including gestational age, birth weight, need for mechanical ventilation, and oxygenation i

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Neonatal Pulmonary Hypertension (NPH) Risk Index: Explanation and Clinical Context The Neonatal Pulmonary Hypertension Risk Index is a validated scoring system designed to stratify the risk of pulmonary hypertension in neonates, particularly preterm infants. It incorporates key clinical variables available shortly after birth, including gestational age, birth weight, need for mechanical ventilation, and oxygenation index. This risk index allows clinicians to identify neonates at low, moderate, or high risk for developing pulmonary hypertension, guiding monitoring intensity and early therapeutic interventions.

The risk score is calculated by assigning points to each risk factor: prematurity (<32 weeks), low birth weight (<1500 grams), requirement for mechanical ventilation, and severe hypoxemia as indicated by a high oxygenation index (>20). The total score stratifies neonates into risk categories to inform clinical decision-making.

Evidence & references1 primary source mapped
  1. Source 1

    Abman SH, et al. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2017;135:e5–e68. doi:10.1161/CIR.0000000000000467

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.