Interactive worksheet
DEFENSE-PFO Model (Cryptogenic Stroke Benefit) Calculator
Patient age (years) Atrial Septal Aneurysm (ASA) present? Septal hypermobility (phasic excursion, mm) High-risk threshold in DEFENSE-PFO: ≥10 mm. PFO separation/height (maximum septum primum–secundum separation, mm) High-risk threshold in DEFENSE-PFO: ≥2 mm. DEFENSE-PFO Model (Cryptogenic Stroke Benefit): Explanation and Clinical Context The DEFENSE-PFO trial evaluated patients with cryptogenic stroke and high-risk p