1,329 calculators and references across 60 specialties, with formula confidence shown up front.
— Explanation and Clinical Context The CANVAS Program (integrated CANVAS and CANVAS-R trials) randomized patients with type 2 diabetes at high cardiovascular risk to canagliflozin versus placebo on top of standard of care. In the integrated analysis the annualized rate of the primary composite (major adverse cardiovascular events — CV death, nonfatal myocardial infarction, or nonfatal stroke) was approximately 31.5 p
— Explanation and Clinical Context This algorithm implements a pragmatic, clinic-level approach to interpreting daily pulmonary artery diastolic (PAD) and (optionally) mean pulmonary artery (PAM) pressure readings obtained from an implanted CardioMEMS™ sensor. The logic uses Merlin.net/Abbott default thresholds when available: a narrow "maintenance" band (PAD ±2 mmHg) where no immediate hemodynamic change is usually
: Explanation and Clinical Context This page implements a configurable logistic risk model intended to predict the probability of heart failure (HF) hospitalization using readily available clinical variables (age, NYHA class, prior HF admission, NT-proBNP, eGFR, systolic blood pressure, heart rate, hemoglobin). The calculator itself does not assume or embed any particular published coefficients; instead it accepts a
— explanation and clinical context This page provides a prototype, point-based risk stratification tool informed by variables central to pulmonary artery pressure-guided heart failure management (age, NYHA class, prior HF hospitalization, mean pulmonary artery pressure, LVEF, renal function, and NT-proBNP). The CHAMPION randomized trial evaluated the CardioMEMS pulmonary artery pressure monitoring system and demonstr
CHARM prognostic model (primary endpoint: cardiovascular death or heart-failure hospitalization — 2-year risk) The CHARM prognostic models were developed using 7,599 patients enrolled in the CHARM programme and identify 21 independent predictors of outcome across the spectrum of left ventricular systolic function. The model forms a linear risk score by summing each predictor multiplied by its coefficient (log hazard)
COMPASS Trial Polyvascular Risk Score — Explanation and clinical context This tool implements the COMPASS trial subgroup framework by counting four high-risk features associated with greater absolute benefit from combined rivaroxaban 2.5 mg twice daily plus aspirin versus aspirin alone: polyvascular disease (≥2 vascular beds affected), renal dysfunction (eGFR < 60 mL/min/1.73m²), a history of heart failure, and diabe
: Explanation, Rationale and Clinical Context This calculator provides a transparent composite index that combines electrical dyssynchrony (QRS duration on surface ECG) and a user-supplied mechanical dyssynchrony measure (for example: septal-to-lateral delay by tissue Doppler, interventricular mechanical delay, or an equivalent echo/TDI-derived delay in milliseconds). The index is not a replacement for guideline-base