Interactive worksheet
CACNA1C Variant Long QT Risk Model Calculator
CACNA1C Variant Long QT Risk Model — Explanation and Clinical Context This tool estimates relative arrhythmic risk in carriers of CACNA1C variants by combining well-recognized predictors from long QT syndrome (LQTS) literature — especially QTc duration and history of syncope or prior cardiac arrest — with gene-specific considerations such as experimentally demonstrated gain-of-function in CACNA1C. QTc elevation, espe