Dual-Energy CT Perfusion Defect Score (PH Correlate) Calculator

Calculator mode This tool supports two peer-reviewed approaches: 1) CTEPH segmental scoring (Abozeed et al., 2022): Perfusion Defect (PD) Score = number of segmental perfusion defects (0–18). Optional “Combined Score” adds clot-burden points (anatomic thrombus load) for stronger correlation with hemodynamics. 2) Perfusion Defect Percentage (Kim et al., 2014): Mean extent of perfusion defect across three coronal planes, estimated in 5% steps; correlates with TR Vmax and pulmonary artery size in pulmonary hypertension of mixed etiologies.

Dual-Energy CT Perfusion Scoring: Explanation and Clinical Context Dual-energy CT (DECT) generates iodine-based perfused-blood-volume (PBV) maps alongside standard CTPA anatomy, enabling semi-quantitative assessment of lung perfusion in pulmonary hypertension (PH). Two validated visual approaches are commonly used at the workstation. The first, designed for chronic thromboembolic PH (CTEPH), defines a Perfusion Defect (PD) Score by counting segmental perfusion defects (0–18) and optionally adds a weighted clot-burden score to form a Combined Score.

The second approach expresses global disease burden as Perfusion Defect Percentage (PD%), averaging the visually estimated defect extent from three coronal planes in 5% increments.