Clinical inputs
Understand the result,
not just the number.
Fick Cardiac Output Calculator Explanation and Clinical Context The Fick principle is one of the most fundamental physiological methods used to determine cardiac output. This calculation is based on the relationship between oxygen consumption and the arteriovenous oxygen content difference. The method assumes that the uptake or release of oxygen by the tissues is equal to the product of blood flow and the arteriovenous oxygen difference.
In clinical practice, oxygen consumption is commonly estimated at one hundred twenty five milliliters per minute per square meter while the oxygen carrying capacity is derived from hemoglobin concentration and oxygen saturation values. Arterial oxygen saturation represents the proportion of hemoglobin that carries oxygen in the arterial system while mixed venous oxygen saturation represents the oxygen content returning to the right heart after systemic extraction. The Fick method is clinically relevant in the evaluation of hemodynamic status, particularly in conditions such as heart failure, pulmonary hypertension, cardiogenic shock, and in patients undergoing right heart catheterization.
A low cardiac output often reflects impaired myocardial contractility, severe valvular disease, or increased systemic oxygen extraction. Conversely, elevated values may occur in sepsis or high output cardiac failure. The Fick technique remains the reference standard in many catheterization laboratories because of its physiological basis and ability to provide accurate cardiac output assessment when assumptions regarding oxygen consumption and sampling conditions are met.
Reference Guyton AC, Hall JE. Textbook of Medical Physiology. Elsevier.
Otto CM, et al. Textbook of Clinical Echocardiography. Elsevier.
Gersh BJ, et al. Braunwald’s Heart Disease. Elsevier.
Haddad F, et al. Cardiac output measurement methods. Circulation.
2008. Rudski LG, et al. Guidelines for right heart assessment.
Journal of the American Society of Echocardiography. 2010.
- Source 1
Dehmer GJ, Firth BG, Hillis LD. Oxygen consumption in adult patients during cardiac catheterization. Clin Cardiol. 1982;5(8):436–440. doi:10.1002/clc.4960050803. Open source
Loading discussion…