Clinical inputs
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Galectin-3 Tertile Risk Model: Explanation and Clinical Context Galectin-3 is a biomarker associated with myocardial fibrosis, inflammation, and adverse remodeling in patients with heart failure. This risk model stratifies patients into tertiles based on circulating Galectin-3 levels to predict prognosis and risk of morbidity and mortality. Tertile 1 represents low risk (<14.1 ng/mL), Tertile 2 represents intermediate risk (14.1–19.9 ng/mL), and Tertile 3 represents high risk (>19.9 ng/mL).
Clinicians can use this tool for risk stratification, guiding therapy, and monitoring disease progression in heart failure patients.
- Source 1
Lok DJ, Van Der Meer P, de la Porte PW, et al. Prognostic value of galectin-3, a novel marker of fibrosis, in patients with chronic heart failure: data from the DEAL-HF study. Clin Res Cardiol. 2010;99(5):323-328. doi:10.1007/s00392-010-0121-2
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