Gensini Score Calculator

About Gensini Score: The Gensini Score is a quantitative angiographic tool used to assess the severity of coronary artery disease (CAD). It considers both the degree of luminal narrowing and the importance of the lesion's location in the coronary tree. Each degree of stenosis (1–25% = 1 point; 26–50% = 2; 51–75% = 4; 76–90% = 8; 91–99% = 16; 100% = 32) is multiplied by a weighting factor based on the anatomic segment (Left Main = 5, Proximal LAD = 2.5, Mid LAD = 1.5, etc.).

Higher scores indicate more severe and extensive coronary atherosclerosis. Clinical Significance: The Gensini Score provides a comprehensive measure of total coronary atherosclerotic burden, often used in clinical research to correlate with biomarkers, left ventricular function, or outcomes after revascularization. It complements other scoring systems such as SYNTAX or Duke CAD Score.

Interpretation Summary: 0 = Normal, 1–20 = Mild CAD, 21–50 = Moderate CAD, >50 = Severe CAD. These ranges may vary depending on institutional standards and research protocols.