HIV-Associated Cardiomyopathy Risk Score Calculator

HIV-Associated Cardiomyopathy Risk Score: Explanation and Clinical Context HIV-associated cardiomyopathy (HIV-CM) represents a spectrum of myocardial dysfunction in individuals living with HIV, driven by multifactorial mechanisms such as chronic immune activation, direct viral injury, ART toxicity, and comorbid cardiovascular risk factors. The proposed scoring model estimates the probability of subclinical or overt cardiomyopathy using accessible clinical parameters including age, immune status (CD4 count), viral load, duration of infection, and traditional cardiovascular risks like hypertension and alcohol use. Clinically, this score assists physicians in identifying HIV-positive patients who may benefit from echocardiographic screening or cardiology referral.

Patients with low CD4 counts, uncontrolled viremia, and prolonged untreated infection exhibit the highest susceptibility. Early ART initiation and optimized blood pressure control significantly reduce cardiomyopathy risk. Interpretation Summary: Low Risk (<10%): Routine follow-up; maintain viral suppression.

Moderate Risk (10–30%): Consider baseline echocardiogram and cardiac biomarker screening. High Risk (>30%): Echocardiographic evaluation and cardiology consultation strongly recommended.