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Vaccination-Associated Cardiac Adverse Event (CAE) Triage Score Calculator

Age (years) Sex (1=Male, 0=Female/Other) Days since most recent vaccination Dose number (1=first, 2=second, 3+=booster) Chest pain present (1=Yes, 0=No) Troponin (multiple of local 99th % ULN) (e.g., 0.8, 1.5, 5) ECG ST/T changes compatible with myocarditis/pericarditis (1=Yes, 0=No) Documented arrhythmia (PVCs, NSVT, VT/VF, atrial arrhythmia) (1=Yes, 0=No) Left ventricular ejection fraction (LVEF, %) (if unknown, en

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Age (years) Sex (1=Male, 0=Female/Other) Days since most recent vaccination Dose number (1=first, 2=second, 3+=booster) Chest pain present (1=Yes, 0=No) Troponin (multiple of local 99th % ULN) (e.g., 0.8, 1.5, 5) ECG ST/T changes compatible with myocarditis/pericarditis (1=Yes, 0=No) Documented arrhythmia (PVCs, NSVT, VT/VF, atrial arrhythmia) (1=Yes, 0=No) Left ventricular ejection fraction (LVEF, %) (if unknown, enter 55) CRP (mg/L) Fever (≥38°C) within 48h of symptom onset (1=Yes, 0=No) Vaccination-Associated Cardiac Adverse Event (CAE) Triage Score: Explanation and Clinical Context This calculator provides a pragmatic, evidence-informed triage score to guide the initial assessment of suspected vaccine-associated myocarditis or pericarditis. It integrates demographic, temporal, clinical, biomarker, ECG, and imaging variables commonly linked to post-vaccination cardiac adverse events. While not a validated diagnostic tool, it reflects current expert consensus and published observations, aiding clinicians in structured risk stratification and triage.

A high score should trigger emergency-level evaluation and cardiology consultation, while a low score suggests outpatient monitoring if symptoms persist.

Evidence & references4 primary sources mapped
  1. Source 1

    Centers for Disease Control and Prevention. Myocarditis after COVID-19 Vaccination: Clinical Considerations. CDC,

  2. Source 2

    Jain SS, et al. Cardiac manifestations and outcomes of vaccine-associated myocarditis in the young (MACoV). eClinicalMedicine (Lancet).

  3. Source 3

    Sandeep N, et al. Myocarditis After COVID-19 Vaccination in Pediatrics. JAHA. 2022;11:e026097. ACC Expert Consensus Decision Pathway on Myocarditis. JACC.

  4. Source 4

    Parmar K, et al. Cardiac Adverse Events after Vaccination—Systematic Review. Vaccines. 2022;10:722.

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Active local worksheet: mapped inputs can be completed, validated, copied, saved, and exported on this device. No numerical score is asserted unless its formula is independently reproducible.

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.