Clinical inputs
Understand the result,
not just the number.
Age (years) Sex (1=Male, 0=Female/Other) Days since most recent vaccination Dose number (1=first, 2=second, 3+=booster) Chest pain present (1=Yes, 0=No) Troponin (multiple of local 99th % ULN) (e.g., 0.8, 1.5, 5) ECG ST/T changes compatible with myocarditis/pericarditis (1=Yes, 0=No) Documented arrhythmia (PVCs, NSVT, VT/VF, atrial arrhythmia) (1=Yes, 0=No) Left ventricular ejection fraction (LVEF, %) (if unknown, enter 55) CRP (mg/L) Fever (≥38°C) within 48h of symptom onset (1=Yes, 0=No) Vaccination-Associated Cardiac Adverse Event (CAE) Triage Score: Explanation and Clinical Context This calculator provides a pragmatic, evidence-informed triage score to guide the initial assessment of suspected vaccine-associated myocarditis or pericarditis. It integrates demographic, temporal, clinical, biomarker, ECG, and imaging variables commonly linked to post-vaccination cardiac adverse events. While not a validated diagnostic tool, it reflects current expert consensus and published observations, aiding clinicians in structured risk stratification and triage.
A high score should trigger emergency-level evaluation and cardiology consultation, while a low score suggests outpatient monitoring if symptoms persist.
- Source 1
Centers for Disease Control and Prevention. Myocarditis after COVID-19 Vaccination: Clinical Considerations. CDC,
- Source 2
Jain SS, et al. Cardiac manifestations and outcomes of vaccine-associated myocarditis in the young (MACoV). eClinicalMedicine (Lancet).
- Source 3
Sandeep N, et al. Myocarditis After COVID-19 Vaccination in Pediatrics. JAHA. 2022;11:e026097. ACC Expert Consensus Decision Pathway on Myocarditis. JACC.
- Source 4
Parmar K, et al. Cardiac Adverse Events after Vaccination—Systematic Review. Vaccines. 2022;10:722.
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