Clinical inputs
Understand the result,
not just the number.
Immune Checkpoint Inhibitor Myocarditis Risk Index: Explanation and Clinical Context This risk index is derived from a multicenter study involving 748 patients treated with immune checkpoint inhibitors (ICIs). The index incorporates five key factors: presence of active thymoma, cardio-muscular symptoms, low QRS voltage on electrocardiogram, left ventricular ejection fraction (LVEF) <50%, and elevated troponin levels. A higher score correlates with an increased risk of severe myocarditis and related adverse cardiac events.
Clinicians can use this tool to stratify patients and tailor management strategies accordingly.
- Source 1
Power JR, Dolladille C, Ozbay B, et al. Immune checkpoint inhibitor-associated myocarditis: a novel risk score. Eur Heart J. 2025;ehaf315. doi:10.1093/eurheartj/ehaf315.
Loading discussion…