Clinical library

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1,329 calculators and references across 60 specialties, with formula confidence shown up front.

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MADIT-CRT Responder Score Calculator

MADIT-CRT Responder Score: Explanation and Clinical Context The MADIT-CRT Responder Score was developed from the Multicenter Automatic Defibrillator Implantation Trial with Cardiac Resynchronization Therapy (MADIT-CRT) to identify heart failure patients most likely to experience reverse left ventricular remodeling and clinical benefit from CRT. This score integrates key predictors including female sex, non-ischemic e

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MADIT-II ICD Mortality Benefit Score (MADIT-ICD Benefit Score)

MADIT-ICD Benefit Score — Explanation and clinical context The MADIT-ICD Benefit Score (Younis et al., 2021) integrates two competing risk scores to predict the likelihood that a patient with low LVEF will derive survival benefit from a prophylactic implantable cardioverter-defibrillator (ICD). The first component estimates the risk of life-threatening ventricular tachyarrhythmia (VT/VF) using eight clinical predicto

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MADIT-RIT Shock Reduction Strategy Index

— Explanation and Clinical Context The MADIT-RIT (Multicenter Automatic Defibrillator Implantation Trial–Reduce Inappropriate Therapy) randomized trial compared three ICD programming strategies designed to minimize unnecessary device therapy: conventional programming (treating tachyarrhythmias starting at ~170 bpm with short detection), high-rate programming (treat only arrhythmias ≥200 bpm), and delayed/duration pro

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MAGGIC Heart Failure Risk Calculator

MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) score: explanation and clinical context The MAGGIC score is an integer-based risk score derived from an individual patient data meta-analysis of >39,000 heart-failure patients and uses 13 routinely available clinical variables to estimate medium-term mortality. The model assigns integer points to age (with points varying by EF band), LVEF categories, systol

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MAGGIC Mortality Risk Score Calculator

MAGGIC Mortality Risk Score: Explanation and Clinical Context The MAGGIC (Meta-Analysis Global Group in Chronic Heart Failure) Risk Score is a validated prognostic model that estimates all-cause mortality in patients with heart failure, developed from data pooled from over 39,000 patients across 30 studies. It incorporates simple, readily available clinical variables such as age, sex, NYHA class, LVEF, systolic blood

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MECKI Score (Cardiopulmonary Exercise + Clinical) Calculator

MECKI Score (Metabolic Exercise test data combined with Cardiac and Kidney Indexes): Explanation and clinical context The MECKI score is a prognostic model developed in a large multicenter registry of patients with heart failure and reduced ejection fraction. It integrates two cardiopulmonary exercise test (CPET) variables—percent predicted peak oxygen uptake (%predicted peak VO2) and VE/VCO2 slope—with routine clini