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Explanation and Clinical Context The SCORE system is a validated clinical tool designed to estimate the ten year risk of fatal cardiovascular events in adults. It was developed from large European cohort datasets and is recommended by several European societies for primary prevention. The SCORE model incorporates age, sex, systolic blood pressure, total cholesterol, and smoking status. These variables are chosen beca
Community ASCVD Screening Yield Calculator: Explanation and Clinical Context This tool estimates the yield and population-level impact of community cardiovascular risk screening followed by statin therapy for primary prevention. Inputs include: average 10-year ASCVD risk among screen-positive individuals, expected LDL-C reduction (mmol/L) with the chosen regimen, treatment uptake, adherence, screen-positivity, and sc
Community Cholesterol Program Impact: Explanation and Clinical Context This calculator estimates the population-level impact of a community cholesterol screening program targeting high-risk individuals. The Absolute Risk Reduction (ARR) is derived from the average 10-year ASCVD risk among screen-positive individuals multiplied by the relative risk reduction (RRR) achievable with statin therapy. The Number Needed to T
Cost-Effectiveness of Statin Therapy by Age/Risk Model: Explanation and Clinical Context This calculator implements a transparent, adjustable cost-effectiveness framework for primary-prevention statin therapy anchored to a patient’s 10-year ASCVD risk and therapy intensity. It estimates absolute risk reduction as baseline risk × RRR and converts events prevented into QALYs. Treatment disutility and excess diabetes ri