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Cardiac Power Output (CPO): Comprehensive Explanation and Clinical Context Cardiac Power Output is a hemodynamic parameter that quantifies the overall pumping capability of the heart by integrating both cardiac output and mean arterial pressure into a single measure. It reflects the amount of hydraulic energy delivered by the heart to circulate blood throughout the body, and it is expressed in Watts. Unlike isolated
Cardiac Power Output Index (CPO Index) Explanation and Clinical Context Cardiac Power Output Index is a hemodynamic parameter that reflects the amount of hydraulic power generated by the heart per unit of body surface area. It is calculated from Cardiac Power Output, which itself is derived from cardiac output and mean arterial pressure. Because it incorporates both flow and pressure components, the CPO Index provide
Cardiohepatic Index (Hepato-renal Risk Composite): Explanation and Clinical Context The Cardiohepatic Index (CHI) is a composite biomarker integrating hepatic and renal dysfunction to predict adverse outcomes in patients with advanced heart failure. It is calculated using serum bilirubin, creatinine, and sodium levels, reflecting the interplay between hepatic congestion, renal impairment, and systemic hemodynamics. E
— Explanation and Clinical Context This algorithm implements a pragmatic, clinic-level approach to interpreting daily pulmonary artery diastolic (PAD) and (optionally) mean pulmonary artery (PAM) pressure readings obtained from an implanted CardioMEMS™ sensor. The logic uses Merlin.net/Abbott default thresholds when available: a narrow "maintenance" band (PAD ±2 mmHg) where no immediate hemodynamic change is usually
Central Aortic Pressure Index (CAPI): Explanation and Clinical Context The Central Aortic Pressure Index (CAPI) represents the ratio of central aortic pressure to peripheral systolic pressure, reflecting the impact of arterial wave reflections and aortic stiffness on central hemodynamics. It is calculated using peripheral systolic pressure (PSP) and augmentation index (AIx), which represents the contribution of refle
CT Pericardial Thickness Index (PTI): Explanation and Clinical Context The CT Pericardial Thickness Index (PTI) is a standardized measure of pericardial thickness adjusted for body surface area (BSA), providing a more individualized assessment of pericardial remodeling or constriction. Pericardial thickening >4 mm/m² is considered abnormal and may indicate constrictive pericarditis or risk for hemodynamic compromise.