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National Amyloidosis Centre (NAC) Risk Score Calculator

National Amyloidosis Centre (NAC) Risk Score: Explanation and Clinical Context The NAC staging system stratifies patients with transthyretin cardiac amyloidosis (ATTR-CA) into prognostic categories based on NT-proBNP and eGFR levels. Stage 1 indicates a lower risk of mortality, while Stage 3 denotes a higher risk. This system aids clinicians in assessing disease severity and guiding treatment decisions.

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National Amyloidosis Centre (NAC) Risk Score: Explanation and Clinical Context The NAC staging system stratifies patients with transthyretin cardiac amyloidosis (ATTR-CA) into prognostic categories based on NT-proBNP and eGFR levels. Stage 1 indicates a lower risk of mortality, while Stage 3 denotes a higher risk. This system aids clinicians in assessing disease severity and guiding treatment decisions.

Evidence & references1 primary source mapped
  1. Source 1

    Nitsche C, et al. Expansion of the National Amyloidosis Centre staging system to detect early mortality risk in transthyretin cardiac amyloidosis. Eur J Heart Fail. 2024;26(7):1234-1242. doi:10.1002/ejhf.2997

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Active local worksheet: mapped inputs can be completed, validated, copied, saved, and exported on this device. No numerical score is asserted unless its formula is independently reproducible.

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.