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QRS Width > 150 ms Response Ratio Calculator

QRS Width >150 ms Response Ratio: Explanation and Clinical Context The QRS Width >150 ms Response Ratio is derived from the MADIT-CRT trial, which studied the effect of cardiac resynchronization therapy (CRT) in patients with mild heart failure and wide QRS complexes. Patients with a QRS duration greater than 150 ms had a significantly higher likelihood of favorable response to CRT compared to those with narrower QRS

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QRS Width >150 ms Response Ratio: Explanation and Clinical Context The QRS Width >150 ms Response Ratio is derived from the MADIT-CRT trial, which studied the effect of cardiac resynchronization therapy (CRT) in patients with mild heart failure and wide QRS complexes. Patients with a QRS duration greater than 150 ms had a significantly higher likelihood of favorable response to CRT compared to those with narrower QRS complexes. The response ratio (~1.64) indicates the relative probability of improvement in left ventricular function and reduction in heart failure events in patients with QRS >150 ms.

This tool helps clinicians estimate the likelihood of CRT efficacy based on baseline QRS duration.

Evidence & references1 primary source mapped
  1. Source 1

    Moss AJ, et al. MADIT-CRT Trial. N Engl J Med. 2009;361:1329-1338. doi:10.1056/NEJMoa0906431

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Active local worksheet: mapped inputs can be completed, validated, copied, saved, and exported on this device. No numerical score is asserted unless its formula is independently reproducible.

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Clinical structure and calculation context point directly to Source 1; additional primary references remain listed for auditability.