Lille Alcoholic Hepatitis Prognosis Score Calculator

Age Albumin day zero g per dL Bilirubin day zero mg per dL Bilirubin day seven mg per dL Prothrombin time seconds Lille Alcoholic Hepatitis Prognosis Score Explanation and Clinical Context The Lille Alcoholic Hepatitis Prognosis Score is an evidence based tool used to evaluate treatment response in patients with severe alcoholic hepatitis who are receiving corticosteroid therapy. The score combines age albumin bilirubin evolution between day zero and day seven and prothrombin time to estimate the likelihood of survival and steroid responsiveness. A lower Lille Score indicates a favorable biological response and is associated with improved short term outcomes while higher values represent poor response and increased mortality risk.

Thresholds are clinically important since a score below zero point four five generally supports continuation of corticosteroid therapy and a score above this value often suggests limited benefit and the need to consider alternative management strategies. Understanding the Lille Score helps clinicians provide individualized prognostic counseling and optimize decision making regarding therapy in a population with significant hepatic vulnerability. Reference Louvet A et al.

The Lille Model Predicts Survival in Patients With Severe Alcoholic Hepatitis Treated With Corticosteroids. Gastroenterology. 2007.