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Age BMI Impaired Fasting Glucose or Diabetes Select Yes No AST ALT Platelet Count Albumin NAFLD Fibrosis Score Explanation and Clinical Context NAFLD Fibrosis Score is a validated noninvasive tool used to estimate the likelihood of advanced liver fibrosis in individuals with nonalcoholic fatty liver disease. The score integrates routine clinical and laboratory variables including age body mass index impaired fasting glucose or diabetes status aspartate aminotransferase alanine aminotransferase platelet count and albumin level. These parameters collectively reflect metabolic stress hepatic inflammation synthetic dysfunction and portal pressure changes.
Lower values typically indicate a low probability of advanced fibrosis while higher values reflect substantial risk which may prompt further evaluation with elastography or biopsy depending on the clinical scenario. This tool supports clinicians in risk stratification therapeutic planning and identifying patients who may benefit from closer follow up or referral to hepatology services. Reference Angulo P et al.
Hepatology 2007 45 846 854.
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