Clinical pathway

Long-COVID, Post-Viral & Post-Infectious Cardiac Models

A focused collection of 15 calculators, scores, and clinical references.

15tools & references
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4C Mortality Score for COVID 19 Calculator

4C Mortality Score for COVID 19 This calculator estimates in hospital mortality risk in patients admitted with COVID 19 using readily available clinical parameters at presentation. 4C Mortality Score for COVID 19 Explanation and Clinical Context The 4C Mortality Score is a validated prognostic tool developed to estimate in hospital mortality risk among patients admitted with COVID 19. It integrates eight routinely av

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Cardiac MRI ECV Persistence Score (Post-Viral Fibrosis Risk) Calculator

Purpose Estimate the probability of persistence of interstitial myocardial fibrosis after viral myocarditis using cardiac MRI parameters. This is an experimental, literature-informed score designed for educational/decision-support use only. It is not a substitute for clinical judgment or formal guidelines. Cardiac MRI ECV Persistence Score: Explanation and Clinical Context This tool provides an experimental composite

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Cardiopulmonary Exercise Test (CPET) Long-COVID Pattern Classifier

CPET Long-COVID Pattern Classifier: Explanation and Clinical Context This tool classifies cardiopulmonary exercise test (CPET) findings in Long-COVID into functional patterns reflecting common physiological derangements, including ventilatory inefficiency, preload failure, chronotropic limitation, gas-exchange impairment, and deconditioning. It integrates established CPET interpretation frameworks and updated post-CO

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Endothelial Dysfunction Post-COVID Index (Biomarker Composite) Calculator

Endothelial Dysfunction Post-COVID Index (Explanation and Clinical Context) This calculator combines validated indices of endothelial stress and an exploratory composite to contextualize post-COVID vascular dysfunction. EASIX = LDH × Creatinine / Platelets — initially validated in hematologic and COVID-19 populations. Higher EASIX correlates with worse endothelial activation and outcomes. Age-adjusted EASIX (aEASIX-C

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Post-acute Myocarditis Persistent Inflammation Score (MRI + Biomarkers) Calculator

Post-acute Myocarditis Persistent Inflammation Score (MRI + Biomarkers): Explanation and Clinical Context This calculator provides a pragmatic, literature-informed composite score to estimate the likelihood of persistent myocardial inflammation after an acute myocarditis episode using follow-up cardiovascular magnetic resonance (CMR) features and blood biomarkers. It weights factors consistently linked with adverse o

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Post-COVID Arrhythmia Risk Model (Autonomic + ECG) Calculator

Post-COVID Arrhythmia Risk Model (Autonomic + ECG): Explanation and Clinical Context This model integrates autonomic markers (HRV indices) and ECG variables to estimate post-acute arrhythmic risk in individuals recovering from COVID-19. Reduced HRV (low SDNN, RMSSD) reflects sympathetic predominance and vagal withdrawal, patterns observed in post-COVID dysautonomia. QTc prolongation captures impaired repolarization r

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Post-COVID Cardiac Symptom Burden Score (Composite) Calculator

Post-COVID Cardiac Symptom Burden Score (Composite): Explanation and Clinical Context This calculator provides a pragmatic composite symptom burden score focused on cardiovascular manifestations reported after SARS-CoV-2 infection. It aggregates nine domains commonly described in post-acute COVID-19 cohorts: dyspnea (rest and exertion), chest pain/pressure, palpitations, dizziness/presyncope, orthostatic intolerance,

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Post-COVID Microvascular Dysfunction Index (Stress Perfusion Surrogate) Calculator

Quantitative CMR Perfusion Inputs (preferred) Enter global myocardial blood flow (MBF) from quantitative CMR perfusion mapping. Post-COVID Microvascular Dysfunction (Stress Perfusion Surrogate): Explanation and Clinical Context This calculator estimates microvascular function using quantitative stress perfusion metrics. The primary output is myocardial perfusion reserve (MPR), computed from global stress and rest myo

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Post-COVID Thrombotic Risk Composite (D-dimer + Clinical) Calculator

Post-COVID Thrombotic Risk Composite (D-dimer + Clinical): Explanation and Clinical Context This calculator applies the IMPROVE-DD model, combining clinical factors with D-dimer elevation (≥2× ULN) to estimate venous thromboembolism (VTE) risk in post-COVID patients. Clinical Significance: High scores identify patients who may benefit from extended prophylaxis with rivaroxaban 10 mg daily for 35 days post-discharge (

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Post-infectious Autoimmune Cardiac Risk Index (Autoantibodies Panel)

: Explanation and Clinical Context Post-infectious autoimmune cardiac disorders represent a spectrum of myocardial and endocardial injury that follows infectious triggers such as viral myocarditis, bacterial infections, or systemic inflammatory responses. The immune system, after pathogen clearance, may continue to recognize cardiac antigens as foreign due to molecular mimicry between microbial epitopes and myocardia

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Return-to-Work Safety Calculator After COVID Cardiac Event

Return-to-Work After COVID Cardiac Event: Explanation and Clinical Context This calculator translates expert consensus recommendations to guide return-to-work (RTW) evaluation following COVID-19–related cardiac events. It focuses on readiness assessment, symptom resolution, biomarker normalization, and absence of active myocardial injury or arrhythmia. It is not a predictive mortality or reinjury risk model but a str

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SARS-CoV-2 Myocarditis Diagnostic Probability (Troponin + MRI + ECG)

ECG Pattern -- choose -- Normal Nonspecific repolarization changes Typical for myocarditis (diffuse ST-T changes / PR depression / new AV block / ventricular arrhythmia) CMR (2018 Lake Louise Criteria) -- choose -- Positive Equivocal / indeterminate Negative Not performed Days from Symptom Onset to CMR (leave blank if CMR not done) SARS-CoV-2 Myocarditis: Explanation and Clinical Context In patients with COVID-19, my

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Vaccine-Related Myocarditis Severity Triage Score (VRMST) Calculator

Vaccine-Related Myocarditis Severity Triage Score (VRMST): Explanation and Clinical Context This calculator estimates bedside severity for suspected vaccine-associated myocarditis using routinely available clinical data. The proposed VRMST score prioritizes factors that consistently track with worse short-term outcomes in myocarditis—hemodynamic instability/shock, depressed left ventricular function, malignant ventri

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Viral Myopericarditis Recurrence Predictor

(proxy using validated recurrent pericarditis models) Enter patient data below to estimate risk strata using a published recurrent pericarditis outcome model. Dedicated, validated scoring systems specifically for viral myopericarditis recurrence are not yet available; therefore, this tool applies the closest validated framework (recurrent pericarditis risk modeling) and should be interpreted in clinical context. Vira