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Cardiac Sarcoidosis Diagnostic Probability Score (HRS adaptation)

: Explanation and Clinical Context This calculator operationalizes the 2014 Heart Rhythm Society (HRS) consensus statement on cardiac sarcoidosis. A definitive diagnosis requires myocardial biopsy showing non-caseating granulomas, whereas a probable diagnosis requires histologically proven extracardiac sarcoidosis plus one or more typical cardiac features and exclusion of other causes. Typical cardiac features includ

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Chagas Disease Cardiac Progression Index (CPI) Calculator

Follow-up horizon (years) Chagas Disease Cardiac Progression Index (CPI): Explanation and Clinical Context This calculator estimates the risk that a patient with Chagas disease will progress to clinically manifest cardiomyopathy over a specified time horizon using pooled annual incidence rates. For individuals with the indeterminate chronic form (no baseline cardiac injury on ECG/echocardiography), the pooled annual

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Endomyocardial Biopsy Yield Predictor (Myocarditis Suspicion Model)

: Explanation and Clinical Context This calculator estimates the probability that an endomyocardial biopsy (EMB) will provide a specific histopathologic or immunohistochemical diagnosis in patients with clinically suspected myocarditis. Diagnostic yield in contemporary cohorts averages around 50–55%, depending on timing, imaging, sampling site, and targeting method. Clinical interpretation Early biopsy (≤14 days), po

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HIV-Associated Cardiomyopathy Risk Score Calculator

HIV-Associated Cardiomyopathy Risk Score: Explanation and Clinical Context HIV-associated cardiomyopathy (HIV-CM) represents a spectrum of myocardial dysfunction in individuals living with HIV, driven by multifactorial mechanisms such as chronic immune activation, direct viral injury, ART toxicity, and comorbid cardiovascular risk factors. The proposed scoring model estimates the probability of subclinical or overt c

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Kawasaki Disease IVIG Resistance (Harada Variant) Calculator

Kawasaki Disease IVIG Resistance (Harada Variant): Explanation and Clinical Context The Harada score is a clinical prediction tool developed to identify patients with Kawasaki Disease (KD) who are at increased risk of resistance to intravenous immunoglobulin (IVIG) therapy. IVIG resistance occurs in approximately 10–20% of KD patients and is associated with persistent fever, prolonged inflammation, and higher risk of

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Lyme Carditis AV Block Risk Score Calculator

Lyme Carditis AV Block Risk Score: Explanation and Clinical Context The Lyme Carditis Suspicious Index (LCI)—also referred to as the Lyme Carditis AV Block Risk Score—was developed by Besant et al. (Circulation: Arrhythmia and Electrophysiology, 2018) to identify patients with high-grade atrioventricular (AV) block secondary to Lyme carditis. The tool assists clinicians in differentiating reversible Lyme carditis fro

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MIS-C Cardiac Severity Index (Cardiogenic Shock Risk) Calculator

MIS-C Cardiac Severity Index (Cardiogenic Shock Risk): Explanation and Clinical Context This calculator applies a validated multivariable model designed to predict cardiogenic shock in children with Multisystem Inflammatory Syndrome (MIS-C). The score is computed as: 0.128 × Age (years) + 1.195 × Dyspnea (1 if present) + 0.007 × CRP (mg/L) − 2.6732. A threshold of −0.4761 distinguishes high- from low-risk patients at

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Sepsis-Related Myocardial Dysfunction (SIMD) Severity Index Calculator

Sepsis-Related Myocardial Dysfunction (SIMD) Severity Index Enter values available at bedside/ICU admission or within the first 24 hours. Use absolute (positive) value for GLS (e.g., 18 = normal strain ~ −18%). Troponin input is expressed as multiple of your lab’s upper limit of normal (ULN). Norepinephrine dose is in µg/kg/min. Sepsis-Related Myocardial Dysfunction (SIMD): Explanation and Clinical Context SIMD (ofte

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TB Pericarditis Complication Risk Model (IMPI-based)

TB Pericarditis Complication Risk Model: Explanation and Clinical Context This calculator estimates a relative hazard index (RHI) for two major complications of tuberculous pericarditis—death and constrictive pericarditis—based on multivariable predictors from the IMPI program. In HIV-infected patients, higher NYHA class, hypotension, peripheral oedema, and lower weight increased mortality hazard. For constrictive pe

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Travel-Related Cardiac Infection Screening Tool (Region-Specific)

Travel Region (primary) Country (optional) Days Since Return Length of Stay (days) Key Exposures (check all that apply) Freshwater swimming/canyoning Heavy mosquito exposure Tick exposure Unpasteurized dairy / farm animal contact Rural/adobe housing (triatomine exposure) Clinical Features (check all that apply) Fever Chest pain Dyspnea Palpitations/syncope New murmur/heart failure signs Eosinophilia Key Tests/History

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Tropical Myocarditis Severity Index (TMSI) – Resource-Limited Adaptation

Tropical Myocarditis Severity Index (TMSI): Explanation and Clinical Context The Tropical Myocarditis Severity Index (TMSI) is a pragmatic bedside score tailored for use in tropical, resource-limited healthcare settings where myocarditis frequently presents secondary to infections such as dengue, rickettsioses, Chagas disease, and leptospirosis. The index prioritizes clinically accessible variables—hemodynamics, arrh

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Vaccination-Associated Cardiac Adverse Event (CAE) Triage Score Calculator

Age (years) Sex (1=Male, 0=Female/Other) Days since most recent vaccination Dose number (1=first, 2=second, 3+=booster) Chest pain present (1=Yes, 0=No) Troponin (multiple of local 99th % ULN) (e.g., 0.8, 1.5, 5) ECG ST/T changes compatible with myocarditis/pericarditis (1=Yes, 0=No) Documented arrhythmia (PVCs, NSVT, VT/VF, atrial arrhythmia) (1=Yes, 0=No) Left ventricular ejection fraction (LVEF, %) (if unknown, en