1,329 calculators and references across 60 specialties, with formula confidence shown up front.
18F-FDG Metabolic Score for Infective Endocarditis (IE): Explanation and Clinical Context The 18F-FDG metabolic score is a semiquantitative PET/CT-based tool used to support the diagnosis of infective endocarditis, particularly in prosthetic or complex valve situations. The score combines valvular uptake intensity, perivalvular uptake, prosthetic valve presence, and timing after surgery to estimate the probability of
2023 Duke ISCVID Diagnostic Criteria for Infective Endocarditis This calculator helps clinicians classify the probability of infective endocarditis based on the updated 2023 Duke ISCVID diagnostic criteria. 2023 Duke ISCVID Diagnostic Criteria for Infective Endocarditis Explanation and Clinical Context The 2023 Duke ISCVID criteria represent an updated and refined diagnostic framework for infective endocarditis incor
AEPEI Score: Explanation and Clinical Context The AEPEI Score is a clinical tool designed to assess the risk of adverse outcomes in patients with prosthetic valve endocarditis. It incorporates three key variables: age, prosthetic valve type, and the presence of extra-cardiac events. A higher score indicates an increased risk of mortality and complications, aiding clinicians in making informed decisions regarding pati
AEPEI Surgical Risk Index: Explanation and Clinical Context The AEPEI Surgical Risk Index is a validated tool designed to estimate perioperative mortality risk in patients undergoing major non-cardiac surgery. It incorporates key patient-specific factors including age, ASA classification, urgency of surgery, heart failure, renal insufficiency, and the complexity of the surgical procedure. The score is calculated by a
CTEP Index: Explanation and Clinical Context The CTEP Index is a scoring system developed to assess the thromboembolic potential in patients with infective endocarditis. It incorporates two key factors: the size of the vegetation and the presence of Staphylococcus aureus as the causative organism. A vegetation size of 13 mm or greater and the identification of Staphylococcus aureus are associated with a higher risk o
DeFeo Score: Explanation and Clinical Context The DeFeo Score is a validated tool to predict the surgical indication in patients with mitral valve disease. It incorporates functional, structural, and hemodynamic parameters: NYHA functional class, left ventricular end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), and pulmonary artery pressure (PAP). Each parameter is assigned points based on t
Denes Prognostic Index (DPI): Explanation and Clinical Context The Denes Prognostic Index is a clinical tool used to assess the mortality risk in patients with infective endocarditis (IE). This index incorporates several key clinical parameters to stratify patients into different risk categories, aiding clinicians in decision-making processes regarding treatment strategies and resource allocation.
DEPOSIT Score: Explanation and Clinical Context The DEPOSIT (Device-related Endocarditis Prediction) Score is a validated tool to estimate the risk of infective endocarditis in patients with cardiac implantable electronic devices (CIEDs). It incorporates patient age, device type (pacemaker, ICD, CRT), prior device-related infections, comorbidities such as diabetes mellitus, and renal failure. Higher scores indicate i
: Explanation and Clinical Context The Modified Duke Criteria is a widely accepted clinical tool for diagnosing infective endocarditis (IE) based on a combination of major and minor criteria. Major criteria include positive blood cultures and evidence of endocardial involvement via echocardiography. Minor criteria include predisposing heart conditions or IV drug use, fever >38°C, vascular phenomena (e.g., arterial em
EASE Score (Early Surgery Benefit in Infective Endocarditis): Explanation and Clinical Context The EASE Score is a clinical tool designed to estimate the potential benefit of early surgical intervention in patients with infective endocarditis (IE). It incorporates age, the presence of Staphylococcus aureus infection, severe heart failure (NYHA class III-IV), and the size of valvular vegetations. The score assigns poi
Embolic Risk Score (Infective Endocarditis): Explanation and Clinical Context The Embolic Risk Score is a validated tool used to estimate the likelihood of systemic embolism in patients with infective endocarditis. It is based on six clinical variables: age > 70 years, diabetes mellitus, atrial fibrillation, previous embolic events, vegetation length > 10 mm, and Staphylococcus aureus infection. Each positive variabl
ENDOVAL Score: Explanation and Clinical Context The ENDOVAL score is a prognostic tool developed to assess in-hospital mortality risk in patients with left-sided infective endocarditis (LSIE) undergoing valve surgery. It incorporates various clinical and microbiological factors to stratify patients into different risk categories, aiding clinicians in decision-making processes regarding surgical interventions.
ESC 2023 Modified Duke Criteria (with PET/CT and MRI): Explanation and Clinical Context The ESC 2023 Modified Duke Criteria integrate clinical, microbiological, and imaging findings to diagnose infective endocarditis (IE) with improved accuracy. Major criteria include positive blood cultures for typical microorganisms, evidence of endocardial involvement on echocardiography, and modern imaging modalities such as PET/
ICE-PCS 6-Month Mortality Risk Model: Explanation and Clinical Context The ICE-PCS 6-Month Mortality Risk Model is a validated tool developed to predict the 6-month mortality risk in patients with infective endocarditis (IE). It incorporates clinical variables such as age, dialysis status, presence of prosthetic or nosocomial IE, left-sided valve vegetation, severe heart failure, stroke, paravalvular complications, a
NOVA Score (Nosocomial vs Community IE): Explanation and Clinical Context The NOVA score is a validated tool designed to differentiate nosocomial infective endocarditis (IE) from community-acquired IE in hospitalized patients. It incorporates four clinical parameters: neutrophil count, organ failure, prosthetic valve presence, and acquisition setting (nosocomial vs community). Each parameter contributes to a total sc
PET-CT Uptake Grading Score: Explanation and Clinical Context The PET-CT Uptake Grading Score is used to quantify the metabolic activity of lesions relative to reference tissues (liver and blood pool) in FDG PET-CT imaging. Grade 0 indicates no significant uptake, Grade 1 indicates low uptake (above blood pool but below liver), Grade 2 indicates moderate uptake (equal to or above liver but less than twice liver SUVme
PETIE Index: Explanation and Clinical Context The PETIE Index is a clinical tool designed to estimate the probability of infective endocarditis (IE) in patients undergoing 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT). This index incorporates the following parameters: - FDG-PET/CT Findings: A positive FDG-PET/CT result is associated with a higher likelihood of IE, contributing 2
Predict Score: Explanation and Clinical Context The Predict Score is a clinical tool designed to estimate the risk of in-hospital mortality in patients with infective endocarditis. Developed through a retrospective analysis of 530 patients, this score incorporates various clinical and laboratory parameters to stratify patients into low, intermediate, or high-risk categories.
RISK-E (Endocarditis Surgery Mortality) Score: Explanation and Clinical Context The RISK-E score is a validated risk prediction tool for estimating operative mortality in patients undergoing surgery for infective endocarditis. It uses preoperative clinical variables, including age, renal failure, NYHA class III-IV heart failure, diabetes mellitus, critical preoperative state, prosthetic valve involvement, emergency s
STS-IE Surgical Risk Model: Explanation and Clinical Context The STS-IE (Society of Thoracic Surgeons – Isolated Valve Surgery) Risk Model is a validated tool to predict postoperative mortality and major morbidity for patients undergoing isolated valve surgery. It uses patient-specific clinical variables including age, sex, previous cardiac surgery, NYHA functional class, left ventricular ejection fraction, diabetes,
VEGF Activity Index (Echo-Based Vegetation Risk): Explanation and Clinical Context The VEGF Activity Index is a validated echocardiography-based tool to assess the risk associated with valvular vegetations in patients with infective endocarditis. It combines key echocardiographic parameters, including vegetation size, mobility, and number, to generate a numeric risk index predictive of embolic events and complication