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1,329 calculators and references across 60 specialties, with formula confidence shown up front.

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CS2 Score (Cardiogenic Shock Survival) Calculator

Explanation and clinical context The CardShock score was developed from a multicenter cohort to predict short-term mortality in patients with cardiogenic shock of various etiologies and uses seven admission variables (age, confusion, previous MI/CABG, ACS as cause, LVEF, lactate and eGFR). The IABP-SHOCK II score was derived from the IABP-SHOCK II trial in AMI-related cardiogenic shock; it uses variables available at

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CT Fractional Flow Reserve (CT FFR) Calculator

CT Fractional Flow Reserve (FFRct): Explanation and Clinical Context CT FFR is a non-invasive imaging-derived estimate of the pressure drop across a coronary stenosis, simulating the fractional flow reserve obtained by invasive measurement. It integrates coronary CT angiography data with computational fluid dynamics (CFD) or simplified algorithms to predict lesion-specific ischemia. FFRct values <0.75 generally indic

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CT Pericardial Thickness Index (PTI) Calculator

CT Pericardial Thickness Index (PTI): Explanation and Clinical Context The CT Pericardial Thickness Index (PTI) is a standardized measure of pericardial thickness adjusted for body surface area (BSA), providing a more individualized assessment of pericardial remodeling or constriction. Pericardial thickening >4 mm/m² is considered abnormal and may indicate constrictive pericarditis or risk for hemodynamic compromise.

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CT-Based Annulus Sizing Index Calculator

CT-Based Annulus Sizing Index: Explanation and Clinical Context The CT-Based Annulus Sizing Index is a quantitative parameter used to assess the relationship between the native aortic annulus size (derived from CT imaging) and the selected transcatheter heart valve (THV) size. It provides an objective measure of oversizing or undersizing during pre-procedural transcatheter aortic valve replacement (TAVR) planning. Th

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CURB65 Pneumonia Severity Score Calculator

CURB65 Pneumonia Severity Score Explanation and Clinical Context CURB65 assigns one point for each of five readily available clinical variables at initial assessment: new onset confusion, blood urea greater than 7 mmol per liter, respiratory rate of 30 breaths per minute or more, low blood pressure defined as systolic less than 90 mm Hg or diastolic 60 mm Hg or less, and age 65 years or older. The total score ranges

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Cushing’s Syndrome Cardiometabolic Risk Score Calculator

Cushing's Syndrome Cardiometabolic Risk Score: Explanation and Clinical Context The Cushing's Syndrome Cardiometabolic Risk Score is a tool designed to quantify the risk of metabolic and cardiovascular complications in patients with endogenous or exogenous hypercortisolism. The score incorporates common metabolic parameters including age, BMI, blood pressure, fasting glucose, triglycerides, and HDL cholesterol to str

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CVP/PCWP Ratio Prognostic Index Calculator

CVP/PCWP Ratio Prognostic Index: Explanation and Clinical Context The CVP/PCWP Ratio Prognostic Index is used to evaluate right and left heart filling pressures in patients with advanced heart failure or cardiogenic shock. Central Venous Pressure (CVP) reflects right atrial pressure, indicating right ventricular preload and venous congestion. Pulmonary Capillary Wedge Pressure (PCWP) reflects left atrial pressure and

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Cystatin C-Based Cardiovascular Mortality Index Calculator

Cystatin C-Based Cardiovascular Mortality Index: Explanation and Clinical Context The Cystatin C-Based Cardiovascular Mortality Index utilizes serum cystatin C levels to estimate glomerular filtration rate (GFR), providing a more accurate assessment of renal function compared to creatinine-based methods. Elevated cystatin C levels have been associated with increased risks of cardiovascular mortality, independent of t

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Cystatin C-NT-proBNP Combined Risk Score Calculator

Cystatin C–NT-proBNP Combined Risk Score: Explanation and Clinical Context The Cystatin C–NT-proBNP Combined Risk Score is designed to stratify patients' cardiovascular risk by integrating renal function (Cystatin C) and cardiac stress marker (NT-proBNP). Elevated Cystatin C reflects impaired kidney function and has been associated with higher cardiovascular morbidity and mortality. NT-proBNP indicates myocardial wal