Clinical library

Every tool, one focused workspace.

1,329 calculators and references across 60 specialties, with formula confidence shown up front.

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Vaccination-Associated Cardiac Adverse Event (CAE) Triage Score Calculator

Age (years) Sex (1=Male, 0=Female/Other) Days since most recent vaccination Dose number (1=first, 2=second, 3+=booster) Chest pain present (1=Yes, 0=No) Troponin (multiple of local 99th % ULN) (e.g., 0.8, 1.5, 5) ECG ST/T changes compatible with myocarditis/pericarditis (1=Yes, 0=No) Documented arrhythmia (PVCs, NSVT, VT/VF, atrial arrhythmia) (1=Yes, 0=No) Left ventricular ejection fraction (LVEF, %) (if unknown, en

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Vaccine-Related Myocarditis Severity Triage Score (VRMST) Calculator

Vaccine-Related Myocarditis Severity Triage Score (VRMST): Explanation and Clinical Context This calculator estimates bedside severity for suspected vaccine-associated myocarditis using routinely available clinical data. The proposed VRMST score prioritizes factors that consistently track with worse short-term outcomes in myocarditis—hemodynamic instability/shock, depressed left ventricular function, malignant ventri

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VACTERL Prognostic Index Calculator

VACTERL Prognostic Index: Explanation and Clinical Context The VACTERL Prognostic Index is a clinical tool developed to predict the likelihood of mortality and the length of hospital stay in neonates diagnosed with VACTERL association. This index is based on the presence of specific congenital anomalies and birth weight, providing healthcare providers with a quantitative measure to assist in counseling and planning c

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VALIANT Heart Failure (LV Dysfunction) Index Calculator

Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction — VALIANT Study: Explanation and clinical context The VALIANT Heart Failure Risk Score was derived from the VALsartan In Acute myocardial iNfarction Trial (VALIANT) cohort and was designed to estimate the risk of first hospitalizati

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VALID-CHF Prognostic Model (CardioWebdr)

VALID-CHF Prognostic Model — Explanation and Clinical Context This page implements a configurable template for the VALID-CHF prognostic model. The final prognostic estimate requires the original VALID-CHF model specification (either logistic regression coefficients or a validated point table). At present the template is prepared so you can paste model coefficients into the PHP array near the top of the file and the s

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Valvular Dysfunction Radiation Index (VDRI) Calculator

Valvular Dysfunction Radiation Index (VDRI): Explanation and Clinical Context The VDRI is a predictive model developed to estimate the risk of radiation-induced valvular heart disease (RVD). It incorporates key factors known to influence the development of RVD, including: - Age at Radiation Exposure: Younger age at the time of radiation therapy is associated with a higher risk of developing RVD later in life. - Radia

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Vascular Remodeling Radiomic Risk Model (FRP) Calculator

Vascular Remodeling Radiomic Risk Model: Explanation and Clinical Context This calculator operationalizes a published perivascular fat radiomic profile (FRP) derived from coronary CT angiography to reflect adverse perivascular adipose tissue remodeling (fibrosis and microvascular changes) that accompanies chronic coronary inflammation. The original model was trained via machine learning (random forest) using hundreds

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Vascular Surgery Cardiac Risk Index (VSG-CRI) Calculator

Vascular Surgery Cardiac Risk Index (VSG-CRI): Explanation and Clinical Context The VSG-CRI is a vascular-surgery–specific risk score developed from >10,000 patients undergoing carotid endarterectomy, lower-extremity bypass, endovascular AAA repair, and open AAA repair. It predicts in-hospital adverse cardiac events (myocardial infarction, arrhythmia, or decompensated heart failure) and was shown to outperform the Re

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Vasoactive-Inotropic Score (VIS) Calculator

Vasoactive-Inotropic Score (VIS): Explanation and Clinical Context The Vasoactive-Inotropic Score (VIS) quantifies the amount of cardiovascular support a patient receives through vasoactive and inotropic medications. It was originally developed to assess post-operative outcomes in pediatric cardiac surgery, correlating higher scores with increased morbidity and mortality. The VIS is calculated as: VIS = dopamine (µg/

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VE/VCO2 Slope Calculator

VE/VCO2 Slope (Ventilatory Efficiency Index): Explanation and Clinical Context VE/VCO2 slope is a measure derived from cardiopulmonary exercise testing (CPET) that quantifies the relationship between minute ventilation (VE) and carbon dioxide output (VCO2) during incremental exercise. It reflects ventilatory efficiency and can indicate abnormal pulmonary ventilation, increased dead space, or poor perfusion–ventilatio

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VEGF Activity Index (Echo-Based Vegetation Risk) Calculator

VEGF Activity Index (Echo-Based Vegetation Risk): Explanation and Clinical Context The VEGF Activity Index is a validated echocardiography-based tool to assess the risk associated with valvular vegetations in patients with infective endocarditis. It combines key echocardiographic parameters, including vegetation size, mobility, and number, to generate a numeric risk index predictive of embolic events and complication

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Ventilatory Threshold (VT1/VT2) Calculator

Ventilatory Thresholds (VT1/VT2): Explanation and Clinical Context Ventilatory thresholds are critical markers in cardiopulmonary exercise testing (CPET) to guide exercise prescription and assess cardiovascular fitness. VT1, the aerobic threshold, represents the exercise intensity at which lactate begins to accumulate above baseline, corresponding approximately to 60% of VO₂ peak. VT2, the anaerobic threshold, indica

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Ventricular Late Potentials (VLP) Score Calculator

Ventricular Late Potentials (VLP) Score: Explanation and Clinical Context Ventricular Late Potentials (VLP) detected on signal-averaged ECG represent delayed depolarization of the ventricular myocardium, typically seen after myocardial infarction. The VLP score uses three parameters: filtered QRS duration (fQRS), low-amplitude signal duration in the terminal 40 ms of QRS (LAS40), and root mean square voltage of the l

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VERTIS-CV Event Prediction (WATCH-DM surrogate) Calculator

VERTIS-CV Event Prediction — implementation notes and clinical context (WATCH-DM surrogate) This tool calculates the integer WATCH-DM score (an externally published, integer-based risk score developed to predict 5-year incident heart-failure hospitalization among patients with type 2 diabetes). WATCH-DM combines routinely available clinical measures (age, BMI, blood pressure), simple blood tests (fasting plasma gluco

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Vienna Prediction Model (DVT Recurrence) Calculator

Vienna Prediction Model for Recurrent Venous Thromboembolism: Explanation and Clinical Context The Vienna Prediction Model is a validated clinical tool designed to predict the 1-year risk of recurrent venous thromboembolism (VTE), particularly deep vein thrombosis (DVT), in patients who have completed initial anticoagulation. The model incorporates three key variables: gender (male vs female), DVT location (proximal

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Villalta Score Calculator for Post Thrombotic Syndrome

Villalta Score for Post Thrombotic Syndrome: Comprehensive Explanation and Clinical Context The Villalta score is a validated clinical tool used to diagnose and grade the severity of Post Thrombotic Syndrome in patients with a history of deep vein thrombosis. It consists of five patient reported symptoms including pain, cramps, heaviness, paresthesia, and pruritus, and six clinician assessed signs including pretibial

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Viral Myopericarditis Recurrence Predictor

(proxy using validated recurrent pericarditis models) Enter patient data below to estimate risk strata using a published recurrent pericarditis outcome model. Dedicated, validated scoring systems specifically for viral myopericarditis recurrence are not yet available; therefore, this tool applies the closest validated framework (recurrent pericarditis risk modeling) and should be interpreted in clinical context. Vira

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Visceral Adiposity Index (VAI) Calculator

Visceral Adiposity Index (VAI): Explanation and Clinical Context Visceral Adiposity Index (VAI) is a gender-specific mathematical model that estimates visceral fat function and distribution using simple anthropometric and metabolic parameters: BMI, waist circumference, triglycerides, and HDL-cholesterol. VAI correlates with cardiometabolic risk and insulin sensitivity, providing a surrogate marker for visceral obesit

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Vital Signs Normal Range Calculator

Explanation and Clinical Context Vital signs represent essential physiological parameters used to assess baseline health status and detect early signs of clinical deterioration. The primary components include heart rate respiratory rate blood pressure and temperature. These values naturally vary across age groups and physiological conditions. In infants normal heart rate and respiratory effort tend to be higher and p

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VO2 Peak Calculator

VO2 Peak: Explanation and Clinical Context VO2 Peak represents the highest attainable oxygen consumption during exercise testing and is widely used as a measure of cardiorespiratory fitness. It reflects the integrated function of the cardiovascular, respiratory, and muscular systems during exertion. Higher VO2 Peak values indicate better aerobic capacity and are associated with lower all cause mortality and cardiovas

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VO2/HR Ratio (Cardiac Efficiency) Calculator

VO₂/HR Ratio (Cardiac Efficiency): Explanation and Clinical Context The VO₂/HR ratio, also known as oxygen pulse, is calculated by dividing oxygen consumption (VO₂) by heart rate (HR) during exercise. It reflects the amount of oxygen ejected by the heart per beat, providing a non-invasive measure of cardiac stroke volume and efficiency. A higher VO₂/HR indicates more efficient cardiac function, whereas a low ratio ma

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VO2/VE Ratio Index Calculator

VO₂/VE Ratio Index: Explanation and Clinical Context The VO₂/VE Ratio Index represents the efficiency of oxygen uptake relative to ventilation during exercise. It is derived from cardiopulmonary exercise testing (CPET) by dividing oxygen consumption (VO₂ in mL/min/kg) by minute ventilation (VE in L/min). A higher VO₂/VE ratio indicates more efficient gas exchange, while a lower ratio suggests ventilatory inefficiency

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VO2/Work Rate (VO2/WR) Slope Calculator

VO₂/Work Rate (VO₂/WR) Slope: Explanation and Clinical Context The VO₂/WR slope quantifies the relationship between oxygen uptake (VO₂, in mL/min) and external work rate (WR, in Watts) during incremental exercise, typically measured during a cardiopulmonary exercise test (CPET). It reflects the efficiency of the cardiovascular and muscular systems in converting oxygen consumption into mechanical work. Normal VO₂/WR s

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VO2max Percentile Rank Calculator

VO₂max Percentile Rank: Explanation and Clinical Context VO₂max, or maximal oxygen uptake, is a key measure of cardiorespiratory fitness. Percentile ranks compare an individual's VO₂max to reference populations of the same age and sex. Higher percentiles indicate better aerobic capacity and lower cardiovascular risk. This tool helps clinicians and fitness professionals estimate fitness levels, stratify cardiovascular

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VOYAGER-PAD Risk Reduction Index Calculator

VOYAGER-PAD Risk Reduction Index: Explanation and Clinical Context The VOYAGER-PAD Risk Reduction Index is a tool derived from the VOYAGER‑PAD Trial dataset, designed to estimate the three-year probability of a composite outcome (acute limb ischemia, major vascular amputation, myocardial infarction, ischemic stroke, or cardiovascular death) among patients undergoing lower-extremity revascularization for symptomatic p

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VSD Size Ratio Index Calculator

VSD Size Ratio Index: Explanation and Clinical Context The Ventricular Septal Defect (VSD) Size Ratio Index is calculated as the ratio of the VSD diameter to the aortic annulus diameter measured on echocardiography. This ratio provides a normalized, dimensionless parameter that allows for interindividual comparison regardless of patient size or age. A VSD/Aortic diameter ratio below 0.3 typically indicates a small de

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VTE-BLEED Score Calculator

VTE-BLEED Score: Explanation and Clinical Context The VTE-BLEED score is a validated clinical tool developed to predict the risk of major bleeding in patients receiving anticoagulant therapy for venous thromboembolism (VTE). It incorporates seven readily available clinical parameters: active cancer, male sex with uncontrolled hypertension, anemia, history of bleeding, age > 60 years, renal dysfunction, and liver dysf