Clinical library

Every tool, one focused workspace.

1,329 calculators and references across 60 specialties, with formula confidence shown up front.

1,329results
Interactive worksheet

ARISTOTLE-based Stroke Risk (Appraisal of Risk in AF) Calculator

Appraisal of Risk in AF (ARISTOTLE-based) Score: Explanation and Clinical Context The ARISTOTLE-based risk score for atrial fibrillation was developed from the ARISTOTLE trial population to predict 1-year risk of stroke or systemic embolism in patients with AF. The model is based on easily obtainable clinical variables including age, prior stroke or transient ischemic attack (TIA), hypertension, diabetes mellitus, an

Interactive worksheet

Arrhythmogenic LV Cardiomyopathy (ALVC) Score Calculator

Arrhythmogenic Left Ventricular Cardiomyopathy (ALVC) Score: Explanation and Clinical Context ALVC Score is a validated risk prediction tool for patients with arrhythmogenic left ventricular cardiomyopathy, aimed at estimating the risk of arrhythmic events over a 5-year period. It incorporates key clinical and imaging parameters, including age, sex, presence of non-sustained ventricular tachycardia (NSVT), left ventr

Interactive worksheet

Arterial Blood Gas Analysis (BGA) Algorithm Calculator

Arterial Blood Gas Interpretation: Explanation and Clinical Context This tool provides a structured approach to identify the primary acid base disturbance and to assess whether the observed respiratory or renal compensation is appropriate for a single predominant disorder. The algorithm first classifies the sample as acidemia or alkalemia based on pH. It then uses the relationship between pCO2 and HCO3 to identify a

Interactive worksheet

ARVC Screening Probability in Athletes (Family History + ECG) Calculator

ARVC Screening Probability in Athletes: Explanation and Clinical Context This calculator assists sports cardiologists in assessing pre-test probability for arrhythmogenic cardiomyopathy (ARVC/ACM) in athletes using key signals: family history and characteristic ECG abnormalities. A first-degree relative with confirmed ARVC or a pathogenic variant markedly raises pre-test suspicion. Similarly, young-age sudden cardiac

Interactive worksheet

ARVC Task Force Criteria (2010 Revised) Calculator

Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Task Force Criteria (2010 Revised): Explanation and Clinical Context The ARVC Task Force Criteria (2010 revised) is a structured diagnostic tool used to improve diagnostic accuracy for ARVC, a genetic cardiomyopathy characterized by fibro-fatty replacement of the right ventricular myocardium, leading to arrhythmias and sudden cardiac death. The criteria are divid

Interactive worksheet

ASCVD 10-Year Risk Estimator

About the : The ASCVD (Atherosclerotic Cardiovascular Disease) 10-Year Risk Estimator is a predictive tool developed by the American College of Cardiology (ACC) and the American Heart Association (AHA) to estimate the probability of a first cardiovascular event (myocardial infarction, stroke, or cardiovascular death) over the next 10 years. It is based on pooled cohort equations derived from large-scale U.S. populati

Interactive worksheet

ASCVD Risk Calculator (Precise for BP Control Target)

Atherosclerotic Cardiovascular Disease (ASCVD) Risk for BP Control Target: Explanation and Clinical Context The ASCVD Risk Score estimates the 10-year risk of atherosclerotic cardiovascular events, including myocardial infarction, stroke, and cardiovascular death, based on the Pooled Cohort Equations developed by the ACC/AHA 2013 guidelines. It incorporates patient-specific factors including age, sex, race, total cho

Interactive worksheet

ASCVD-DM Subscore Calculator

ASCVD-DM Subscore: Explanation and Clinical Context The ASCVD-DM Subscore is a clinical tool designed to estimate the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) specifically in patients with type 2 diabetes mellitus. It incorporates traditional ASCVD risk factors such as age, sex, total cholesterol, HDL cholesterol, systolic blood pressure, antihypertensive treatment, smoking status, and diabetes

Interactive worksheet

ASCVD-Hypertension Submodel Calculator

ASCVD-Hypertension Submodel: Explanation and Clinical Context The ASCVD-Hypertension Submodel is a validated tool developed by the American College of Cardiology/American Heart Association to estimate the 10-year risk of atherosclerotic cardiovascular disease (ASCVD) in patients with hypertension. It incorporates demographic factors (age, sex, race), lipid profile (total cholesterol, HDL cholesterol), systolic blood

Interactive worksheet

ASD Closure Complication Risk (TEE-based Model) Calculator

ASD Closure Complication Risk (TEE-based Model): Explanation and Clinical Context This tool integrates TEE-derived anatomical predictors associated with adverse outcomes during transcatheter secundum ASD closure, translating them into a structured heuristic for clinical use. The strongest predictor for erosion is the coexistence of aortic rim deficiency and device oversizing > 5 mm. Additional features—multiple rim d

Interactive worksheet

ASPECTS (Alberta Stroke Program Early CT Score) Calculator

ASPECTS (Alberta Stroke Program Early CT Score): Explanation and Clinical Context The Alberta Stroke Program Early CT Score (ASPECTS) is a 10-point quantitative CT-based scoring system designed to detect and quantify early ischemic changes within the middle cerebral artery (MCA) territory on non-contrast head CT. The MCA territory is divided into ten defined regions (four subcortical: caudate head [C], lentiform nucl

Interactive worksheet

AST/ALT Ratio Prognostic Index Calculator

AST/ALT Ratio (De Ritis Ratio): Explanation and Clinical Context The AST/ALT ratio, also known as the De Ritis ratio, is a simple but valuable biomarker used in the assessment of liver injury and prognosis. It was first described by Fernando De Ritis in 1957 as the ratio between serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT). A ratio less than 1 typically indicates acute hepatocellular inju

Interactive worksheet

ASTRAL Score Calculator

ASTRAL Score: Explanation and Clinical Context The ASTRAL Score is a validated clinical tool designed to predict 90-day functional outcome after acute ischemic stroke. It integrates six key variables available at hospital admission: age, NIHSS stroke severity, time from symptom onset to admission, range of neurological deficit, arterial territory involved, and serum glucose levels. The total score allows stratificati

Formula reviewed

Atherogenic Index of Plasma (AIP) Calculator

Atherogenic Index of Plasma (AIP): Explanation and Clinical Context The Atherogenic Index of Plasma (AIP) is calculated as the base-10 logarithm of the ratio of plasma triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C) in mmol/L: log10(TG/HDL-C). It serves as a sensitive marker of plasma atherogenicity and is closely associated with the size of LDL particles, with higher AIP indicating a predominance

Score mapped

Athletic Heart vs Pathology Differentiation Score (Echo + ECG)

: Explanation and Clinical Context This tool is intended to assist clinicians in distinguishing physiological cardiac adaptation in athletes (“athlete’s heart”) from potentially pathological conditions such as hypertrophic cardiomyopathy, dilated cardiomyopathy, or arrhythmogenic right ventricular cardiomyopathy. The score integrates key features from resting ECG (e.g., T-wave inversion, pathological Q waves, bundle

Score mapped

ATRIA Bleeding Score Calculator

ATRIA Bleeding Score: Explanation and Clinical Context The ATRIA Bleeding Score (Anticoagulation and Risk Factors in Atrial Fibrillation) is a validated risk stratification tool designed to estimate the annual risk of major bleeding in patients with atrial fibrillation (AF) receiving oral anticoagulant therapy. Developed from a cohort of over 13,000 AF patients in the ATRIA study, it incorporates five independent pre

Interactive worksheet

ATRIA Stroke Risk Score Calculator

ATRIA Stroke Risk Score: Explanation and Clinical Context The ATRIA Stroke Risk Score is a validated clinical tool to predict the risk of ischemic stroke in patients with atrial fibrillation. It uses common patient characteristics including age, sex, history of diabetes mellitus, heart failure, hypertension, and prior stroke/TIA. Scores are calculated by assigning points to each risk factor, resulting in a total scor

Interactive worksheet

Atrial Pacing Burden (% Time Pacing) Calculator

Atrial Pacing Burden (% Time Pacing): Explanation and Clinical Context Atrial Pacing Burden represents the percentage of time a patient’s atrium is paced by a pacemaker relative to the total number of heartbeats recorded. High atrial pacing burden has been associated with increased risk of atrial fibrillation, heart failure progression, and potentially adverse cardiovascular outcomes. Clinically, quantifying atrial p

Interactive worksheet

AUDIT C Alcohol Use Screening Calculator

AUDIT C Alcohol Use Screening Explanation and Clinical Context AUDIT C is a validated three item alcohol screening tool designed to rapidly identify patterns of drinking that may represent hazardous or harmful alcohol use. It evaluates how often a person drinks alcoholic beverages alongside the number of drinks typically consumed and how frequently episodes of heavy drinking occur. Each question contributes zero to t

Interactive worksheet

AUGUSTUS Antithrombotic Strategy Calculator

AUGUSTUS Antithrombotic Strategy – Explanation and Clinical Context The AUGUSTUS randomized trial (2×2 factorial) compared apixaban versus a vitamin K antagonist and aspirin versus placebo in patients with atrial fibrillation and recent acute coronary syndrome and/or percutaneous coronary intervention who were taking a P2Y12 inhibitor. The principal findings were that apixaban (vs VKA) reduced clinically relevant ble

Interactive worksheet

AVSD Surgical Mortality Score Calculator

AVSD Surgical Mortality Score: Explanation and Clinical Context The AVSD Surgical Mortality Score is a predictive tool to estimate the risk of operative mortality in patients undergoing repair for atrioventricular septal defect (AVSD). It incorporates key preoperative variables, including age, weight, presence of Down syndrome, preoperative ventricular dysfunction, and pulmonary hypertension. The score uses a logisti

Reference

Bacterial Meningitis Diagnostic Tool

Age Cerebrospinal Fluid Glucose CSF Glucose mg per dL Cerebrospinal Fluid Protein CSF Protein mg per dL Cerebrospinal Fluid White Blood Cell Count CSF WBC cells per mm3 Blood Glucose mg per dL Explanation and Clinical Context This tool assists clinicians by providing a structured evaluation of the probability of bacterial meningitis using variables derived from cerebrospinal fluid studies and basic laboratory measure

Interactive worksheet

Balloon Pulmonary Angioplasty (BPA) Success Score Calculator

Balloon Pulmonary Angioplasty (BPA) Success Score: Explanation and Clinical Context Balloon Pulmonary Angioplasty (BPA) is an interventional therapy for patients with inoperable or residual chronic thromboembolic pulmonary hypertension (CTEPH). The BPA Success Score estimates the likelihood of achieving hemodynamic normalization (mean pulmonary artery pressure < 25 mmHg) following a series of BPA sessions. The score

Interactive worksheet

BASDAI Ankylosing Activity Index Calculator

BASDAI Ankylosing Activity Index Explanation and Clinical Context The Bath Ankylosing Spondylitis Disease Activity Index is a validated instrument used to quantify disease activity in ankylosing spondylitis. This tool evaluates six core symptoms that include fatigue spinal pain peripheral joint pain enthesitis and two measures related to morning stiffness. Each component reflects a central aspect of inflammatory burd

Interactive worksheet

BASIL Trial Risk Model Calculator

BASIL Trial Risk Model: Explanation and Clinical Context The BASIL Trial Risk Model is derived from the multicenter BASIL trial comparing surgical bypass and angioplasty in patients with severe limb ischemia. This model estimates 1-year mortality risk based on key clinical factors including age >75, male sex, renal dysfunction, severe cardiac disease, tissue loss (ulcer or gangrene), and urgency of the procedure. Eac

Interactive worksheet

BASMI Mobility Score Calculator

BASMI Mobility Score Explanation and Clinical Context BASMI or Bath Ankylosing Spondylitis Metrology Index is a standardized instrument used to quantify spinal and hip mobility limitation in patients with axial spondyloarthritis. The score is derived from five physical measurements which include cervical rotation tragus to wall distance lumbar side flexion lumbar flexion evaluated with the modified Schober test and i

Interactive worksheet

BCN Bio-HF Calculator

BCN Bio-HF (approximate implementation): Explanation and context The BCN Bio-Heart Failure (BCN Bio-HF) risk calculator is a multimarker prognostic tool developed from a contemporary outpatient heart-failure cohort. It combines routine clinical variables (age, NYHA class, LVEF, sodium, eGFR, hemoglobin, loop diuretic dose, and evidence-based treatments such as beta-blocker/ACEI/ARB/statin) with up to three serum biom

Interactive worksheet

Beck Anxiety and Depression Variants Calculator

Beck Depression Inventory One Score Beck Depression Inventory Two Score Beck Anxiety Inventory Score Beck Hopelessness Scale Score Beck Anxiety and Depression Variants Explanation and Clinical Context Beck psychological assessment tools are widely validated instruments used to quantify the severity of anxiety depression and hopelessness in clinical and research settings. Beck Depression Inventory One and Beck Depress

Interactive worksheet

Bernstein-Parsonnet 2000 Risk Model Calculator

Bernstein-Parsonnet 2000 Risk Model: Explanation and Clinical Context The Bernstein-Parsonnet 2000 Model is a validated scoring system designed to estimate operative mortality risk in patients undergoing cardiac surgery. It incorporates patient-specific variables including age, gender, left ventricular ejection fraction (LVEF), New York Heart Association (NYHA) functional class, history of previous cardiac surgery, a

Interactive worksheet

Bilirubin/Albumin Ratio (BAR Index) Calculator

Bilirubin/Albumin Ratio (BAR Index): Explanation and Clinical Context The Bilirubin/Albumin Ratio (BAR) is a biochemical marker that reflects the balance between liver excretory function (represented by serum bilirubin) and synthetic capacity (represented by albumin). An elevated BAR value indicates an imbalance between hepatocellular injury and decreased albumin synthesis, both of which are associated with systemic

Interactive worksheet

BioHF Score (Heart Failure Biomarker Risk) Calculator

BioHF Score: Explanation and Clinical Context The BioHF Score (modelled after the BCN Bio-HF Calculator) integrates clinical variables (age, sex, NYHA class, LVEF, serum sodium, eGFR, hemoglobin, loop diuretic dose, and therapy status such as β-blocker, ACEI/ARB, statin) together with key biomarkers (NT-proBNP, high-sensitivity troponin T, and soluble ST2) to estimate individual mortality risk at 1, 2 and 3 years in

Interactive worksheet

Bioimpedance Scale Body Fat Calculator

Bioimpedance Scale Body Fat Explanation and Clinical Context Bioimpedance scales estimate body fat percentage by analyzing the resistance of body tissues to a low level electrical current. Lean tissue contains more water and conducts electricity more easily, whereas fat tissue provides higher resistance. Consumer bioimpedance devices combine anthropometric variables such as height, weight, age, and sex to improve est

Interactive worksheet

BIOSTAT-CHF Mortality Risk (Approximation) Calculator

BIOSTAT-CHF Mortality Risk: Explanation and Clinical Context The BIOSTAT-CHF (A systems BIOlogy Study to Tailored Treatment in Chronic Heart Failure) program developed and validated multivariable risk models for outcomes in heart failure using a large European cohort (index n≈2,516; validation n≈1,738). The five strongest independent predictors of all-cause mortality were: older age, higher blood urea nitrogen (BUN),

Score mapped

BISAP Pancreatitis Mortality Score Calculator

BISAP Pancreatitis Mortality Score Explanation and Clinical Context The BISAP Score is a validated early risk stratification tool for predicting mortality in acute pancreatitis. The score incorporates five clinical parameters that can be measured within the first twenty four hours of hospital evaluation. These parameters include blood urea nitrogen elevation impaired mental status systemic inflammatory response syndr

Interactive worksheet

Bishop Score Labour Induction Calculator

Explanation and Clinical Context The Bishop score is a clinical tool used to assess cervical favorability for labour induction by assigning points to five parameters assessed on digital cervical examination: cervical dilation, effacement, fetal station, cervical consistency, and cervical position. Each parameter contributes a subscore. The total score ranges from zero to thirteen. Higher scores indicate a cervix that

Interactive worksheet

Blatchford GI Bleeding Score Calculator

Glasgow Blatchford Score Explanation and Clinical Context The Glasgow Blatchford Score is a preendoscopic risk stratification tool for patients with acute upper gastrointestinal bleeding. It uses clinical and basic laboratory variables available at presentation to estimate the likelihood that a patient will need hospital based intervention such as blood transfusion endoscopic therapy or surgery. The score components

Interactive worksheet

Bleeding Risk after Cardiac Surgery (Papworth BRiSc) Calculator

Surgery Type -- Select -- CABG or Single Valve Other (e.g., double/triple valve, aortic, combined) Aortic Valve Disease (stenosis/regurgitation) -- Select -- No Yes BMI (kg/m2) Age (years) Bleeding Risk after Cardiac Surgery (Papworth BRiSc): Explanation and Clinical Context This calculator implements the Papworth Bleeding Risk Score (BRiSc), a preoperative stratification tool developed to identify cardiac surgery pa

Interactive worksheet

Bleeding Risk vs Ischemic Benefit DAPT Balance Tool

Explanation and Clinical Context Dual antiplatelet therapy combining aspirin and a P2Y12 receptor inhibitor is a cornerstone of treatment after acute coronary syndromes. The 2025 American Heart Association acute coronary syndromes guideline emphasizes that the intensity and duration of antiplatelet therapy should be individualized by balancing ischemic benefit against bleeding risk within a structured clinical decisi

Interactive worksheet

Blood Pressure Mean and Category Calculator

Explanation and Clinical Context Mean Arterial Pressure is an important physiological value that reflects average arterial pressure within one cardiac cycle. It approximates perfusion pressure to vital organs such as brain heart and kidney. MAP is commonly calculated using the formula SBP plus two times DBP divided by three. Normal MAP values generally range from seventy to one hundred millimeter mercury. Values belo

Interactive worksheet

Blood Urea Nitrogen/Creatinine Ratio (BUN/Cr) Risk Class Calculator

Blood Urea Nitrogen/Creatinine (BUN/Cr) Ratio: Explanation and Clinical Context The BUN/Cr ratio is a commonly used biochemical marker to assess the relative elevation of blood urea nitrogen compared to serum creatinine. It is widely applied in the context of acute kidney injury (AKI), volume depletion, and other renal and systemic conditions. A BUN/Cr ratio <10 is generally considered low risk, indicating a low like

Formula reviewed

BMI Based Body Fat Percentage Calculator

BMI Based Body Fat Percentage Explanation and Clinical Context BMI based body fat estimation uses body mass index, age, and sex to approximate total body fat percentage. This method is derived from population based regression models and provides a simple alternative when direct body composition measurement is unavailable. Body mass index reflects the relationship between body weight and height but does not differenti

Formula reviewed

BMR TDEE Body Composition Calculator Suite

Explanation and clinical context Basal metabolic rate estimated by the Mifflin St Jeor equation reflects resting energy expenditure in adults and is widely used due to its accuracy across different populations. Total daily energy expenditure combines basal metabolic rate with an activity factor to estimate energy needs for weight maintenance. Adjustments for weight gain or loss typically use a fifteen percent change

Interactive worksheet

BNP Elevation Risk Tier (Cardiotoxicity Marker) Calculator

BNP Elevation Risk Tier (Cardiotoxicity Marker): Explanation and Clinical Context B-type Natriuretic Peptide (BNP) is a cardiac neurohormone released in response to ventricular volume expansion and pressure overload. Elevated BNP levels in patients undergoing potentially cardiotoxic therapies, such as anthracyclines or trastuzumab, may indicate early myocardial stress and subclinical cardiotoxicity. BNP risk stratifi

Interactive worksheet

BNP/Creatinine Ratio Index Calculator

BNP/Creatinine Ratio Index: Explanation and Clinical Context The BNP/Creatinine Ratio is a biomarker-based index used in patients with heart failure and renal dysfunction to assess cardiovascular risk more precisely. Elevated BNP reflects cardiac stress, whereas serum creatinine indicates renal function. Combining these parameters accounts for the confounding effect of renal impairment on BNP levels, enhancing progno

Interactive worksheet

BNP/NT-proBNP Cutoffs Stratified for PH (Calculator)

Value Enter numeric value in ng/L (e.g., 275 or 275.5). Risk Model -- choose -- ESC/ERS 3-Strata (Low / Intermediate / High) COMPERA 2.0 Four-Strata (Low / Intermediate-Low / Intermediate-High / High) BNP/NT-proBNP Cutoffs in Pulmonary Hypertension: Explanation and Clinical Context Brain natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) are key biomarkers of right ventricular strain and adverse prognosis i

Interactive worksheet

BNP/NT-proBNP Ratio Index Calculator

BNP/NT-proBNP Ratio Index: Explanation and Clinical Context The BNP/NT-proBNP Ratio Index provides additional insight into the biochemical phenotype of heart failure and helps to differentiate between acute and chronic heart failure presentations. Both BNP and NT-proBNP are derived from proBNP, but they differ in clearance mechanisms and biological half-life. BNP is biologically active and cleared mainly by natriuret

Interactive worksheet

BNP/NT-proBNP Risk Tier Calculator

BNP/NT-proBNP Risk Tier: Explanation and Clinical Context The BNP/NT-proBNP Risk Tier is a validated system to classify patients according to the circulating levels of B-type natriuretic peptide (BNP) or N-terminal pro-BNP (NT-proBNP). These biomarkers reflect myocardial wall stress, ventricular overload, and cardiac dysfunction in conditions such as pulmonary arterial hypertension (PAH) and heart failure. Levels are